People

Current Lab Members


Michael J. Harms, PhD
Principal Investigator
Assistant Professor
Chemistry & Biochemistry
Institute of Molecular Biology
harms@uoregon.edu
541-346-9002 (Office)
541-346-9003 (Lab)

Mike grew up in Oregon, attending Oregon State University for his undergraduate degree in Biochemistry/Biophysics.  He earned a PhD in molecular biophysics under Bertrand Garcia-Moreno E. at Johns Hopkins University.  He then accidentally returned to Oregon to do postdoctoral studies in molecular evolution with Joe Thornton. He hasn’t left yet.Hobbies: spends time with his beautiful wife and two boys.  Road bikes and does photography in his (copious amounts of) free time.
Curriculum Vitae
IMB PageGoogle Scholar Profile
ResearchGate
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Luke Wheeler
PhD student, Biochemistry
541-346-9003 (Lab phone)
Luke was born in the rain shadow of the Cascades and subsequently grew up in central Oregon. A PhD student in the chemistry program, he is currently using ancestral sequence reconstruction, phage display, next-generation sequencing, and biophysical approaches to understand the evolution of peptide binding specificity in the S100 protein family. He earned an undergraduate degree in biochemistry from Montana State University where he did undergraduate research on the encapsulation of various peptides into the interior of virus-like particles. When not in lab, he unicycles, hikes, and takes pictures of wildlife including, but not limited to, snakes, lizards and very annoying storks.
Andrea Loes
Andrea Loes

PhD Student, Biochemistry
541-346-9003 (Lab phone)
Andrea brings an interest in bacterial communities and transition metal ecology to the lab. She is currently studying the evolution of calprotectin, a multi-functional heterodimer of S100A8 and S100A9 that sequesters Mn(II) and Zn(II) in the mammalian gut, playing roles in innate immunity, inflammation, and cell motility. She completed undergraduate degrees in microbiology and biochemistry at Arizona State University, where she did undergraduate research studying antimicrobial activity of clay mineral mixtures and inhibition kinetics of the urease of Staphylococcus saprophyticus. When not growing microorganisms in the lab, she uses them at home to brew beer.
Zach Sailer
Zach Sailer
PhD Student, Physical chemistry
541-346-9003 (Lab phone)
Zach is using conceptual and computational tools developed for studying physical chemical systems to study how the structure of protein sequence space shapes protein evolution.  He brings a strong background in scientific computing and software development to the lab, having completed a degree in physics at Cal Poly and then working as a developer on the IPython/Jupyter platform.  When not programming at work, he programs at home because, why not?  And no, we have no idea what’s going on in his picture.
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Joseph Harman
PhD Student, Biochemistry
541-346-9003 (Lab phone)
 Joseph grew up in Mississippi before heading out west, where he received his bachelor’s degree in biochemistry from Willamette University. His undergraduate research at Willamette focused on designing a fluorescent probe for monitoring changes in the oxidation state of a ruthenium-based anti-cancer drug, NAMI-A. Now a student in the chemistry and biochemistry PhD program at UO, he is studying the evolution and underlying biophysical properties of heterocomplex formation between S100 proteins S100A8 and S100A9, which form a multifunctional complex in humans called calprotectin. Outside of the lab, Joseph enjoys sports and spending his time at Oregon’s many beautiful lakes, rivers, and mountains.
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Anneliese Morrison
PhD Student
541-346-9003 (Lab phone)
Anneliese earned an undergraduate degree in biochemistry from Florida State University where she studied the adaptation of Microvirid bacteriophages to biophysical selective pressures. Now a PhD student in UO’s biochemistry program, she is studying how the structure and underlying properties of protein sequence space shape the evolution of new functions. When not in the lab, Anneliese enjoys exploring the pacific northwest and continuing the quest to find the world’s best donut.
Hiranmayi Duvvuri
541-346-9003 (Lab phone)
Bram Rickett
Undergraduate
541-346-9003 (Lab phone)
Ran Shi
Undergraduate
541-346-9003 (Lab phone)
Caitlyn Wong
Undergraduate
541-346-9003 (Lab phone)
Matt Wong
Undergraduate
541-346-9003 (Lab phone)